NMS presentation disorientated, diaphoretic, high temp, tachycardia, tachypnea, rigidity, high wbs, elevated CPK rhabdomyolysis breakdown of muscle tissue releasing a damaging protein in the blood greatest risk for NMS high potency antipsychotics like haldol Lithium labs creatinine, BUN, electrolytes, thyroid, urinalysis lithium excreted 95% by kidneys lithium inhibits synthesis of thyroid medication delayed therapeutic effects of serotonin may be due to down-regulation of post-synaptic 5-HT2 receptor sites mild serotonin syndrome looks like tachycardia, flushing, fever, hypertension, ocular oscillations, myoclonic jerks severe serotonin syndrome looks like hyperthermia, coma, convulsions, autonomic instability, and death if taking an MAOI, you must wait how long before taking another agent 14 days Opisthotonos a condition in which a person holds their body in an abnormal position.
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